2013 · CLINICAL NUCLEAR MEDICINE

18F-Fluoride PET/CT Aspect of an Unusual Case of Erdheim-Chester Disease With Histologic Features of Langerhans Cell Histiocytosis

Caoduro, Cecile, Ungureanu, Constantin Marius, Rudenko, Boris, Angoue, Orland, Blagosklonov, Oleg, Paycha, Frederic, Boulahdour, Hatem

Journal
CLINICAL NUCLEAR MEDICINE
Année
2013
Volume
38
Numéro
7
Pages
541-542
Mois
JUL
DOI
10.1097/RLU.0b013e318270830f

Abstract

We report the case of a 63-year-old woman with Erdheim-Chester disease (ECD) and histologic features of Langerhans cell histiocytosis, both extremely rare histiocytic proliferations responsible of skeletal and extraskeletal involvement. F-18-Fluoride PET/CT revealed multiple intense focal uptake scattered throughout the skeleton. We also performed an F-18-FDG PET/CT which point out visceral and vascular involvement. This case illustrates the interest of PET/CT in ECD, a rare polymorphus and systemic disease, and in our knowledge, this is the first reported illustration of F-18-fluoride PET/CT findings in this pathology.

Lire l'article complet