- Journal
- CLINICAL NUCLEAR MEDICINE
- Année
- 2009
- Volume
- 34
- Numéro
- 1
- Pages
- 20-23
- Mois
- JAN
- DOI
- 10.1097/RLU.0b013e31818f4355
Abstract
A 38-year-old man presented with an inflammatory polysynovitis involving the knees, ankles, hands, and shoulders, which appeared I year after bone marrow transplantation for chronic myeloid leukemia worsening. The diagnostic considerations included incipient iatrogenic or autoimmune inflammatory rheumatism, joint leukemia relapse, osteoarthritis, and joint chronic graft-versus-host disease (cGVHD). MRI appeared to be osteomyelitis. Radionuclide imaging suggested joint cGVHD diagnosis, which was confirmed by pathologic and microbiological studies, disclosing osteonecrosis but no rheumatoid, oncological, or infectious pattern. One-year follow-up showed clinical improvement under infliximab therapy and confirmed the diagnosis of joint cGVHD.