2017 · CLINICAL NUCLEAR MEDICINE

Brain Perfusion Before and After Surgical Treatment of Moyamoya Disease

Drouet, Clement, Morel, Olivier, Thines, Laurent, Porot, Clemence, Boulahdour, Hatem

Journal
CLINICAL NUCLEAR MEDICINE
Année
2017
Volume
42
Numéro
5
Pages
E269-E272
Mois
MAY
DOI
10.1097/RLU.0000000000001606

Abstract

Moyamoya disease is characterized by bilateral progressive terminal internal carotid arteries steno-occlusion. In this patient, the disease affected middle cerebral arteries and was disclosed after a left frontal cerebral infarction. Brain HMPAO perfusion scintigraphy with acetazolamide challenge, obtained before surgical treatment, demonstrates an extended bilateral frontal hypoperfusion with a vascular steal phenomenon. The same examination obtained after surgical treatment demonstrates a frank improvement in basal brain vascularization, with nearly complete correction of vascular steal phenomenon. HMPAO brain scintigraphy is a very useful tool in the assessment of moyamoya disease severity before surgery and for the evaluation of treatment efficiency.

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