- Journal
- EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
- Année
- 2016
- Volume
- 14
- Numéro
- 12
- Pages
- 1179-1194
- Mois
- DEC
- DOI
- 10.1080/14787210.2016.1240030
Abstract
Introduction: The use of various types of invasive interventions combined with anti-infective drugs in the therapeutic strategy of alveolar echinococcosis (AE) has changed during the last 30years.Areas covered: This article reviews the current respective indications of surgical, percutaneous and perendoscopic interventions in AE and proposes an integrative therapeutic strategy.Expert commentary: Hepatic resection is indicated whenever it is feasible and curative; palliative surgery should be avoided; percutaneous procedures are best adapted to the drainage of the necrotic cavity present in advanced cases; perendoscopic procedures with stenting are best adapted to alleviating the biliary complications that are common and life-threatening in AE patients. Continuous administration of albendazole or mebendazole, without interruption is mandatory in all cases, temporarily (recommended duration: 2years) after radical lesion resection in patients without immune suppression; for life in all other cases. Long-term follow-up is essential.