- Journal
- ORGANIC LETTERS
- Année
- 2019
- Volume
- 21
- Numéro
- 20
- Pages
- 8364-8368
- Mois
- OCT 18
- DOI
- 10.1021/acs.orglett.9b03139
Abstract
O-(omega-Alkynyl) hydroxamates derived from cyclobutenyl carboxylic acids were identified as viable substrates in intramolecular rhodium(III)-catalyzed hetero-annulations, which led to diversely substituted cyclobuta[c]pyridones. Further functionalization of the resulting cyclobutapyridones enabled the synthesis of cyclobuta[c]pyridines and other nitrogen heterocycles after electrocyclic ring opening of the four-membered ring.