2007 · ORGANIC LETTERS

Stereoselective synthesis of 1,2-aminoalcohols by [2,3]-Wittig rearrangements

Barbazanges, Marion, Meyer, Christophe, Cossy, Janine

Journal
ORGANIC LETTERS
Année
2007
Volume
9
Numéro
17
Pages
3245-3248
Mois
AUG 16
DOI
10.1021/ol0711725

Abstract

[2,3]-Wittig rearrangements of (E)-3-aza-allylic alcohol derivatives can provide access to functionalized 1,2-aminoalcohols with high syn or anti diastereoselectivity depending on the anionic stabilizing group (amide or alkyne).

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