- Journal
- ORGANIC LETTERS
- Année
- 2015
- Volume
- 17
- Numéro
- 11
- Pages
- 2800-2803
- Mois
- JUN 5
- DOI
- 10.1021/acs.orglett.5b01205
Abstract
Electron-deficient ynamides, possessing an ynoate or an ynone moiety, have been successfully involved for the first time in a 1,3-dipolar cycloaddition with stabilized pyridinium ylides. These reactions afford an efficient and general access toward a variety of substituted 2-aminoindolizines which can serve as useful precursors for the synthesis of other more complex nitrogen heterocycles.